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The disulfide loop of gp41 is critical to the furin recognition site of HIV gp160
The importance of the HIV gp41 conserved disulfide loop to envelope function has been examined by mutational and functional analyses. Based on a luciferase-reporter entry assay, mutants gp41-CC/AA (C598A/C604A) and gp41-Δ (deletion of residues 596–606) result in a nonfunctional envelope protein. Wes...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206660/ https://ncbi.nlm.nih.gov/pubmed/17525470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072771407 |
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