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Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells

Exposure to high levels of glucose and iron are co-related to reactive oxygen species (ROS) generation and dysregulation of insulin synthesis and secretion, although the precise mechanisms are not well clarified. The focus of this study was to examine the consequences of exposure to high iron levels...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Blesia, Voni, Patel, Vinood B., Al-Obaidi, Hisham, Renshaw, Derek, Zariwala, Mohammed Gulrez
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151797/
https://ncbi.nlm.nih.gov/pubmed/34065122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051141
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