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Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells

Exposure to high levels of glucose and iron are co-related to reactive oxygen species (ROS) generation and dysregulation of insulin synthesis and secretion, although the precise mechanisms are not well clarified. The focus of this study was to examine the consequences of exposure to high iron levels...

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發表在:Cells
Main Authors: Blesia, Voni, Patel, Vinood B., Al-Obaidi, Hisham, Renshaw, Derek, Zariwala, Mohammed Gulrez
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151797/
https://ncbi.nlm.nih.gov/pubmed/34065122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051141
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