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Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells

Exposure to high levels of glucose and iron are co-related to reactive oxygen species (ROS) generation and dysregulation of insulin synthesis and secretion, although the precise mechanisms are not well clarified. The focus of this study was to examine the consequences of exposure to high iron levels...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Blesia, Voni, Patel, Vinood B., Al-Obaidi, Hisham, Renshaw, Derek, Zariwala, Mohammed Gulrez
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151797/
https://ncbi.nlm.nih.gov/pubmed/34065122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051141
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