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HIV-1 Envelope Conformation, Allostery, and Dynamics

The HIV-1 envelope glycoprotein (Env) mediates host cell fusion and is the primary target for HIV-1 vaccine design. The Env undergoes a series of functionally important conformational rearrangements upon engagement of its host cell receptor, CD4. As the sole target for broadly neutralizing antibodie...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Bennett, Ashley Lauren, Henderson, Rory
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150877/
https://ncbi.nlm.nih.gov/pubmed/34067073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050852
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