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A borane-mediated palladium-catalyzed reductive allylic alkylation of α,β-unsaturated carbonyl compounds

The development of the palladium-catalyzed allylic alkylation of in situ generated boron enolates via tandem 1,4-hydroboration is reported. Investigation of the reaction revealed insights into specific catalyst electronic features as well as a profound leaving group effect that proved crucial for ac...

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Publié dans:Chem Sci
Auteurs principaux: Trost, Barry M., Zuo, Zhijun, Schultz, Johnathan E., Anugula, Nagaraju, Carr, Katherine A.
Format: Artigo
Langue:Inglês
Publié: The Royal Society of Chemistry 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150111/
https://ncbi.nlm.nih.gov/pubmed/34123302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05970a
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