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Enantioselective Synthesis of α-tertiary Hydroxyaldehydes by Palladium-Catalyzed Asymmetric Allylic Alkylation of Enolates

Chiral α-tertiary hydroxyaldehydes are very versatile building blocks in synthetic chemistry. Herein, we reported the first examples of a catalytic asymmetric protocol for the synthesis of such compounds from readily available α-halo or α-hydroxy ketones or enol silyl ethers with excellent yields an...

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Autori principali: Trost, Barry M., Xu, Jiayi, Reichle, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533583/
https://ncbi.nlm.nih.gov/pubmed/17212401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja067342a
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