Target identification among known drugs by deep learning from heterogeneous networks

Without foreknowledge of the complete drug target information, development of promising and affordable approaches for effective treatment of human diseases is challenging. Here, we develop deepDTnet, a deep learning methodology for new target identification and drug repurposing in a heterogeneous dr...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Zeng, Xiangxiang, Zhu, Siyi, Lu, Weiqiang, Liu, Zehui, Huang, Jin, Zhou, Yadi, Fang, Jiansong, Huang, Yin, Guo, Huimin, Li, Lang, Trapp, Bruce D., Nussinov, Ruth, Eng, Charis, Loscalzo, Joseph, Cheng, Feixiong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society of Chemistry 2020
Konular:
Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150105/
https://ncbi.nlm.nih.gov/pubmed/34123272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04336e
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