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Network-based prediction of drug–target interactions using an arbitrary-order proximity embedded deep forest

MOTIVATION: Systematic identification of molecular targets among known drugs plays an essential role in drug repurposing and understanding of their unexpected side effects. Computational approaches for prediction of drug–target interactions (DTIs) are highly desired in comparison to traditional expe...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Zeng, Xiangxiang, Zhu, Siyi, Hou, Yuan, Zhang, Pengyue, Li, Lang, Li, Jing, Huang, L Frank, Lewis, Stephen J, Nussinov, Ruth, Cheng, Feixiong
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203727/
https://ncbi.nlm.nih.gov/pubmed/31971579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa010
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