Network-based prediction of drug–target interactions using an arbitrary-order proximity embedded deep forest

MOTIVATION: Systematic identification of molecular targets among known drugs plays an essential role in drug repurposing and understanding of their unexpected side effects. Computational approaches for prediction of drug–target interactions (DTIs) are highly desired in comparison to traditional expe...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Zeng, Xiangxiang, Zhu, Siyi, Hou, Yuan, Zhang, Pengyue, Li, Lang, Li, Jing, Huang, L Frank, Lewis, Stephen J, Nussinov, Ruth, Cheng, Feixiong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203727/
https://ncbi.nlm.nih.gov/pubmed/31971579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa010
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