Network-based prediction of drug–target interactions using an arbitrary-order proximity embedded deep forest

MOTIVATION: Systematic identification of molecular targets among known drugs plays an essential role in drug repurposing and understanding of their unexpected side effects. Computational approaches for prediction of drug–target interactions (DTIs) are highly desired in comparison to traditional expe...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Zeng, Xiangxiang, Zhu, Siyi, Hou, Yuan, Zhang, Pengyue, Li, Lang, Li, Jing, Huang, L Frank, Lewis, Stephen J, Nussinov, Ruth, Cheng, Feixiong
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Original Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203727/
https://ncbi.nlm.nih.gov/pubmed/31971579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa010
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