Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy

Diabetic nephropathy (DN) is characterized by sterile inflammation with continuous injury and loss of renal inherent parenchyma cells. Podocyte is an essential early injury target in DN. The injury and loss of podocytes are closely associated with proteinuria, the early symptom of renal injury in DN...

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Udgivet i:Acta Pharmacol Sin
Main Authors: Cheng, Qian, Pan, Jing, Zhou, Zhuan-li, Yin, Fan, Xie, Hong-yan, Chen, Pan-pan, Li, Jing-yao, Zheng, Pei-qing, Zhou, Li, Zhang, Wei, Liu, Jun, Lu, Li-min
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149386/
https://ncbi.nlm.nih.gov/pubmed/32968210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00525-z
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