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A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer
Many cancers have developed resistance to 5-FU, due to removal by the enzyme uracil-DNA glycosylase (UDG), a type of base excision repair enzyme (BER) that can excise uracil and 5-fluorouracil (5-FU) from DNA. However, the development of UDG inhibitor screening methods, especially for the rapid and...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Chem Sci |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Royal Society of Chemistry
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8148385/ https://ncbi.nlm.nih.gov/pubmed/34123270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05623h |
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