Uracil-DNA glycosylases preferentially excise mispaired uracil.

We have investigated the substrate specificity of human, viral and bacterial uracil-DNA glycosylases employing as substrate double-stranded oligonucleotides containing in the same position of the 5'-32P-labelled strand an uracil residue facing, on the complementary strand, guanine (mimicking cy...

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Bibliographic Details
Main Authors: Verri, A, Mazzarello, P, Spadari, S, Focher, F
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133107/
https://ncbi.nlm.nih.gov/pubmed/1359874
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