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Effect of the enamine pyramidalization direction on the reactivity of secondary amine organocatalysts

Chiral secondary amines are valuable catalysts for reactions that proceed through an enamine intermediate. Here, we explored the importance of the pyramidalization direction of the enamine-N on the reactivity of chiral enamines with a combination of computational, NMR spectroscopic, and kinetic expe...

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Publicat a:Chem Sci
Autors principals: Schnitzer, Tobias, Möhler, Jasper S., Wennemers, Helma
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148379/
https://ncbi.nlm.nih.gov/pubmed/34123288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05410c
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