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Effect of the enamine pyramidalization direction on the reactivity of secondary amine organocatalysts

Chiral secondary amines are valuable catalysts for reactions that proceed through an enamine intermediate. Here, we explored the importance of the pyramidalization direction of the enamine-N on the reactivity of chiral enamines with a combination of computational, NMR spectroscopic, and kinetic expe...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Schnitzer, Tobias, Möhler, Jasper S., Wennemers, Helma
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148379/
https://ncbi.nlm.nih.gov/pubmed/34123288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05410c
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