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The Evolution of Antisense Oligonucleotide Chemistry—A Personal Journey

Over the last four decades, tremendous progress has been made in use of synthetic oligonucleotides as therapeutics. This has been possible largely by introducing chemical modifications to provide drug like properties to oligonucleotides. In this article I have summarized twists and turns on use of c...

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Bibliografske podrobnosti
izdano v:Biomedicines
Glavni avtor: Agrawal, Sudhir
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147625/
https://ncbi.nlm.nih.gov/pubmed/34063675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050503
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