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The Evolution of Antisense Oligonucleotide Chemistry—A Personal Journey

Over the last four decades, tremendous progress has been made in use of synthetic oligonucleotides as therapeutics. This has been possible largely by introducing chemical modifications to provide drug like properties to oligonucleotides. In this article I have summarized twists and turns on use of c...

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Detalhes bibliográficos
Publicado no:Biomedicines
Autor principal: Agrawal, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147625/
https://ncbi.nlm.nih.gov/pubmed/34063675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050503
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