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Vaccination with Prion Peptide-Displaying Polyomavirus-Like Particles Prolongs Incubation Time in Scrapie-Infected Mice

Prion diseases like scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt–Jakob disease (CJD) in humans are fatal neurodegenerative diseases characterized by the conformational conversion of the normal, mainly α-helical cellular prion protein (PrP(C)) into the abnormal β-...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Eiden, Martin, Gedvilaite, Alma, Leidel, Fabienne, Ulrich, Rainer G., Groschup, Martin H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147134/
https://ncbi.nlm.nih.gov/pubmed/33946367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050811
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