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Membrane Cholesterol Dependence of Cannabinoid Modulation of Glycine Receptor

Cannabinoids exert therapeutic effects on several diseases such as chronic pain and startle disease by targeting glycine receptors (GlyRs). Our previous studies have shown that cannabinoids target a serine residue at position 296 in the third transmembrane helix of the α1/α3 GlyR. This site is locat...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Yao, Lei, Wells, Marta, Wu, Xiongwu, Xu, Yan, Zhang, Li, Xiong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147113/
https://ncbi.nlm.nih.gov/pubmed/32608538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903093R
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