Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

Certain types of nonpsychoactive cannabinoids can potentiate glycine receptors (GlyRs), an important target for nociceptive regulation at the spinal level. However, little is known about the potential and mechanism of glycinergic cannabinoids for chronic pain treatment. We report that systemic and i...

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Main Authors: Xiong, Wei, Cui, Tanxing, Cheng, Kejun, Yang, Fei, Chen, Shao-Rui, Willenbring, Dan, Guan, Yun, Pan, Hui-Lin, Ren, Ke, Xu, Yan, Zhang, Li
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371734/
https://ncbi.nlm.nih.gov/pubmed/22585736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120242
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