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Membrane Cholesterol Dependence of Cannabinoid Modulation of Glycine Receptor

Cannabinoids exert therapeutic effects on several diseases such as chronic pain and startle disease by targeting glycine receptors (GlyRs). Our previous studies have shown that cannabinoids target a serine residue at position 296 in the third transmembrane helix of the α1/α3 GlyR. This site is locat...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Yao, Lei, Wells, Marta, Wu, Xiongwu, Xu, Yan, Zhang, Li, Xiong, Wei
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147113/
https://ncbi.nlm.nih.gov/pubmed/32608538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903093R
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