Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease

Circulating neuronal extracellular vesicles (NEVs) of Alzheimer’s disease (AD) patients show high Tau and β-amyloid (Aβ) levels, whereas their astrocytic EVs (AEVs) contain high complement levels. To validate EV proteins as AD biomarkers, we immunocaptured NEVs and AEVs from plasma collected from fi...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Delgado-Peraza, Francheska, Nogueras-Ortiz, Carlos J., Volpert, Olga, Liu, Dong, Goetzl, Edward J., Mattson, Mark P., Greig, Nigel H., Eitan, Erez, Kapogiannis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146429/
https://ncbi.nlm.nih.gov/pubmed/33922642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10050993
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