Walking Speed Decline in Older Adults is Associated with Elevated Pro-BDNF in Plasma Extracellular Vesicles

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is produced by cleavage of proBDNF, and BDNF and proBDNF may play antagonistic roles in nervous system development, learning, memory and neuronal stress resistance. BDNF and proBDNF are present in blood, but the origin and relative contributions o...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Suire, Caitlin, Eitan, Erez, Shaffer, Nancy Chiles, Tian, Qu, Studenski, Stephanie, Mattson, Mark P., Kapogiannis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642035/
https://ncbi.nlm.nih.gov/pubmed/28843509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.08.024
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