Walking Speed Decline in Older Adults is Associated with Elevated Pro-BDNF in Plasma Extracellular Vesicles

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is produced by cleavage of proBDNF, and BDNF and proBDNF may play antagonistic roles in nervous system development, learning, memory and neuronal stress resistance. BDNF and proBDNF are present in blood, but the origin and relative contributions o...

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Vydáno v:Exp Gerontol
Hlavní autoři: Suire, Caitlin, Eitan, Erez, Shaffer, Nancy Chiles, Tian, Qu, Studenski, Stephanie, Mattson, Mark P., Kapogiannis, Dimitrios
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642035/
https://ncbi.nlm.nih.gov/pubmed/28843509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.08.024
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