Walking Speed Decline in Older Adults is Associated with Elevated Pro-BDNF in Plasma Extracellular Vesicles

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is produced by cleavage of proBDNF, and BDNF and proBDNF may play antagonistic roles in nervous system development, learning, memory and neuronal stress resistance. BDNF and proBDNF are present in blood, but the origin and relative contributions o...

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Bibliografiske detaljer
Udgivet i:Exp Gerontol
Main Authors: Suire, Caitlin, Eitan, Erez, Shaffer, Nancy Chiles, Tian, Qu, Studenski, Stephanie, Mattson, Mark P., Kapogiannis, Dimitrios
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642035/
https://ncbi.nlm.nih.gov/pubmed/28843509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.08.024
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