Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice

Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific rigor and reproducibility. In these studies, adul...

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Опубликовано в: :J Am Assoc Lab Anim Sci
Главные авторы: Russell, Lauren N, Hyatt, William S, Gannon, Brenda M, Simecka, Christy M, Randolph, Mildred M, Fantegrossi, William E
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for Laboratory Animal Science 2021
Предметы:
Husbandry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145121/
https://ncbi.nlm.nih.gov/pubmed/33888181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-JAALAS-20-000093
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