Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice

Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific rigor and reproducibility. In these studies, adul...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Assoc Lab Anim Sci
Hauptverfasser: Russell, Lauren N, Hyatt, William S, Gannon, Brenda M, Simecka, Christy M, Randolph, Mildred M, Fantegrossi, William E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for Laboratory Animal Science 2021
Schlagworte:
Husbandry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145121/
https://ncbi.nlm.nih.gov/pubmed/33888181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-JAALAS-20-000093
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