Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice

Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific rigor and reproducibility. In these studies, adul...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Assoc Lab Anim Sci
Main Authors: Russell, Lauren N, Hyatt, William S, Gannon, Brenda M, Simecka, Christy M, Randolph, Mildred M, Fantegrossi, William E
Format: Artigo
Jezik:Inglês
Izdano: American Association for Laboratory Animal Science 2021
Teme:
Husbandry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145121/
https://ncbi.nlm.nih.gov/pubmed/33888181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-JAALAS-20-000093
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