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Effects of Laboratory Housing Conditions on Core Temperature and Locomotor Activity in Mice

Drug developers worldwide assess compound safety and efficacy using measures that include mouse core temperature and locomotor activity. Subtle differences in animal housing conditions between institutions can alter these values, impacting scientific rigor and reproducibility. In these studies, adul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Assoc Lab Anim Sci
Prif Awduron: Russell, Lauren N, Hyatt, William S, Gannon, Brenda M, Simecka, Christy M, Randolph, Mildred M, Fantegrossi, William E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for Laboratory Animal Science 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145121/
https://ncbi.nlm.nih.gov/pubmed/33888181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-JAALAS-20-000093
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