Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives

Histone deacetylases (HDACs) and bromodomain-containing proteins (BCPs) play a key role in chromatin remodeling. Based on their ability to regulate inducible gene expression in the context of inflammation and cancer, HDACs and BCPs have been the focus of drug discovery efforts, and numerous small-mo...

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Bibliographic Details
Published in:J Pers Med
Main Authors: Ghiboub, Mohammed, Elfiky, Ahmed M. I., de Winther, Menno P. J., Harker, Nicola R., Tough, David F., de Jonge, Wouter J.
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145108/
https://ncbi.nlm.nih.gov/pubmed/33922725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11050336
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