Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives

Histone deacetylases (HDACs) and bromodomain-containing proteins (BCPs) play a key role in chromatin remodeling. Based on their ability to regulate inducible gene expression in the context of inflammation and cancer, HDACs and BCPs have been the focus of drug discovery efforts, and numerous small-mo...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Ghiboub, Mohammed, Elfiky, Ahmed M. I., de Winther, Menno P. J., Harker, Nicola R., Tough, David F., de Jonge, Wouter J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145108/
https://ncbi.nlm.nih.gov/pubmed/33922725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11050336
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