Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

Colorectal cancer (CRC) originates as consequence of multiple genetic alterations. Some of the involved genes have been extensively studied (APC, TP53, KRAS, SMAD4, PIK3CA, MMR genes) in highly heterogeneous and poly-metastatic cohorts. However, about 10% of metastatic CRC patients presents with an...

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Bibliografische gegevens
Gepubliceerd in:Transl Oncol
Hoofdauteurs: Ottaiano, Alessandro, Santorsola, Mariachiara, Caraglia, Michele, Circelli, Luisa, Gigantino, Valerio, Botti, Gerardo, Nasti, Guglielmo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2021
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144733/
https://ncbi.nlm.nih.gov/pubmed/34034007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101131
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