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Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

Colorectal cancer (CRC) originates as consequence of multiple genetic alterations. Some of the involved genes have been extensively studied (APC, TP53, KRAS, SMAD4, PIK3CA, MMR genes) in highly heterogeneous and poly-metastatic cohorts. However, about 10% of metastatic CRC patients presents with an...

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Bibliografski detalji
Izdano u:Transl Oncol
Glavni autori: Ottaiano, Alessandro, Santorsola, Mariachiara, Caraglia, Michele, Circelli, Luisa, Gigantino, Valerio, Botti, Gerardo, Nasti, Guglielmo
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144733/
https://ncbi.nlm.nih.gov/pubmed/34034007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101131
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