Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

Colorectal cancer (CRC) originates as consequence of multiple genetic alterations. Some of the involved genes have been extensively studied (APC, TP53, KRAS, SMAD4, PIK3CA, MMR genes) in highly heterogeneous and poly-metastatic cohorts. However, about 10% of metastatic CRC patients presents with an...

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Detalles Bibliográficos
Publicado en:Transl Oncol
Main Authors: Ottaiano, Alessandro, Santorsola, Mariachiara, Caraglia, Michele, Circelli, Luisa, Gigantino, Valerio, Botti, Gerardo, Nasti, Guglielmo
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2021
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144733/
https://ncbi.nlm.nih.gov/pubmed/34034007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101131
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