Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

Colorectal cancer (CRC) originates as consequence of multiple genetic alterations. Some of the involved genes have been extensively studied (APC, TP53, KRAS, SMAD4, PIK3CA, MMR genes) in highly heterogeneous and poly-metastatic cohorts. However, about 10% of metastatic CRC patients presents with an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transl Oncol
Prif Awduron: Ottaiano, Alessandro, Santorsola, Mariachiara, Caraglia, Michele, Circelli, Luisa, Gigantino, Valerio, Botti, Gerardo, Nasti, Guglielmo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2021
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144733/
https://ncbi.nlm.nih.gov/pubmed/34034007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101131
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