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Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats
The orbitofrontal cortex–ventromedial striatum (OFC–VMS) circuitry is widely believed to drive compulsive behavior. Hyperactivating this pathway in inbred mice produces excessive and persistent self-grooming, which has been considered a model for human compulsivity. We aimed to replicate these findi...
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| Veröffentlicht in: | Transl Psychiatry |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8144623/ https://ncbi.nlm.nih.gov/pubmed/34031365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01448-x |
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