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OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics

Several OPRD1 intronic variants were associated with opioid addiction (OD) in a population-specific manner. This follow-up study aims to further characterize the OPRD1 haplotype pattern of the risk variants in different populations and apply in silico analysis to identify potential causal variants....

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Levran, Orna, Randesi, Matthew, Adelson, Miriam, Kreek, Mary Jeanne
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144180/
https://ncbi.nlm.nih.gov/pubmed/34031368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01439-y
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