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CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction
Adequate methadone dosing in methadone maintenance treatment (MMT) for opioid addiction is critical for therapeutic success. One of the challenges in dose determination is the inter-individual variability in dose response. Methadone metabolism is attributed primarily to cytochrome P450 enzymes CYP3A...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735354/ https://ncbi.nlm.nih.gov/pubmed/21790905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2011.00349.x |
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