Nerve growth factor beta polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment

Opioid addiction is a chronic disease with high genetic contribution and a large inter-individual variability in therapeutic response. The goal of this study was to identify pharmacodynamic factors that modulate methadone dose requirement. The neurotrophin family is involved in neural plasticity, le...

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Bibliographische Detailangaben
Hauptverfasser: Levran, Orna, Peles, Einat, Hamon, Sara, Randesi, Matthew, Zhao, Connie, Zhang, Bin, Adelson, Miriam, Kreek, Mary Jeanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130093/
https://ncbi.nlm.nih.gov/pubmed/21358750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.6
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