African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction

AIM: This study was designed to determine whether polymorphisms in acetylcholine receptors contribute to opioid dependence and/or cocaine dependence. PATIENTS & METHODS: The sample (n = 1860) was divided by drug and ancestry, and 55 polymorphisms (nine genes) were analyzed. RESULTS: Of the 20 SN...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Levran, Orna, Randesi, Matthew, Peles, Einat, Correa da Rosa, Joel, Ott, Jurg, Rotrosen, John, Adelson, Miriam, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996315/
https://ncbi.nlm.nih.gov/pubmed/27269905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2016-0028
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