Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry

BACKGROUND: Drug addiction, a leading health problem, is a chronic brain disease with a significant genetic component. Animal models and clinical studies established the involvement of glutamate and GABA neurotransmission in drug addiction. This study was designed to assess if 258 variants in 27 gen...

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Veröffentlicht in:Prog Neuropsychopharmacol Biol Psychiatry
Hauptverfasser: Levran, Orna, Peles, Einat, Randesi, Matthew, da Rosa, Joel Correa, Ott, Jurg, Rotrosen, John, Adelson, Miriam, Kreek, Mary Jeanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564302/
https://ncbi.nlm.nih.gov/pubmed/26277529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2015.08.003
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