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The power of modelling pulsatile profiles
The quantitative description of individual observations in non-linear mixed effects models over time is complicated when the studied biomarker has a pulsatile release (e.g. insulin, growth hormone, luteinizing hormone). Unfortunately, standard non-linear mixed effects population pharmacodynamic mode...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8144129/ https://ncbi.nlm.nih.gov/pubmed/33660229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-021-09743-2 |
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