Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

The phenotype of coeliac disease varies considerably for incompletely understood reasons. We investigated whether established coeliac disease susceptibility variants (SNPs) are individually or cumulatively associated with distinct phenotypes. We also tested whether a polygenic risk score (PRS) based...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Hum Genet
Hlavní autoři: Cerqueira, Juliana X. M., Saavalainen, Päivi, Kurppa, Kalle, Laurikka, Pilvi, Huhtala, Heini, Nykter, Matti, L. E. Koskinen, Lotta, Yohannes, Dawit A., Kilpeläinen, Elina, Shcherban, Anastasia, Palotie, Aarno, Kaukinen, Katri, Lindfors, Katri
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144013/
https://ncbi.nlm.nih.gov/pubmed/33446885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-020-00888-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky