Gut-Liver physiomimetics reveal paradoxical modulation of IBD-related inflammation by short-chain fatty acids

Association between the microbiome, IBD and liver diseases are known, yet cause and effect remain elusive. By connecting human microphysiological systems of the gut, liver and circulating Treg/Th17 cells, we created a multi-organ model of ulcerative colitis (UC) ex vivo. The approach shows microbiom...

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Publicado en:Cell Syst
Main Authors: Trapecar, Martin, Communal, Catherine, Velazquez, Jason, Alexander Maass, Christian, Huang, Yu-Ja, Schneider, Kirsten, Wright, Charles W., Butty, Vincent, Eng, George, Yilmaz, Omer, Trumper, David, Griffith, Linda G.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143761/
https://ncbi.nlm.nih.gov/pubmed/32191873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.02.008
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