Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases

Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled in vitro systems to investigate organ-organ– and organ-immune–specific interactions relevant for disease pathophysiology. Of particular interest is the gut/microbiome-liver-brain axis f...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Trapecar, Martin, Wogram, Emile, Svoboda, Devon, Communal, Catherine, Omer, Attya, Lungjangwa, Tenzin, Sphabmixay, Pierre, Velazquez, Jason, Schneider, Kirsten, Wright, Charles W., Mildrum, Samuel, Hendricks, Austin, Levine, Stuart, Muffat, Julien, Lee, Meelim Jasmine, Lauffenburger, Douglas A., Trumper, David, Jaenisch, Rudolf, Griffith, Linda G.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846169/
https://ncbi.nlm.nih.gov/pubmed/33514545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd1707
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