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Low-dose theophylline in addition to ICS therapy in COPD patients: A systematic review and meta-analysis
BACKGROUND: A synergism has been reported between theophylline and corticosteroids, wherein theophylline increases and restores the anti-inflammatory effect of inhaled corticosteroids (ICS) by enhancing histone deacetylase-2 (HDAC) activity. Several studies have explored the efficacy of low-dose the...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8143407/ https://ncbi.nlm.nih.gov/pubmed/34029327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251348 |
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