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An Ex Vivo and In Silico Study Providing Insights into the Interplay of Circulating miRNAs Level, Platelet Reactivity and Thrombin Generation: Looking beyond Traditional Pharmacogenetics

Platelet reactivity (PR), a key pharmacodynamic (PD) component of the action of antiplatelet drugs in cardiovascular disease (CVD) patients, is highly variable. PR is associated with occurrence or recurrence of thrombotic and bleeding events, but this association is modulated by several factors. Con...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Garcia, Alix, Dunoyer-Geindre, Sylvie, Nolli, Séverine, Reny, Jean-Luc, Fontana, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143175/
https://ncbi.nlm.nih.gov/pubmed/33919053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11050323
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