In silico and in vitro pharmacogenetic analysis in mice

Combining the experimental efficiency of a murine hepatic in vitro drug biotransformation system with in silico genetic analysis produces a model system that can rapidly analyze interindividual differences in drug metabolism. This model system was tested by using two clinically important drugs, test...

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Detalhes bibliográficos
Main Authors: Guo, Yingying, Lu, Peng, Farrell, Erin, Zhang, Xun, Weller, Paul, Monshouwer, Mario, Wang, Jianmei, Liao, Guochun, Zhang, Zhaomei, Hu, Steven, Allard, John, Shafer, Steve, Usuka, Jonathan, Peltz, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077071/
https://ncbi.nlm.nih.gov/pubmed/17978195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700724104
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