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Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption

Recent concepts suggest that both Plasmodium falciparum factors and coagulation contribute to endothelial activation and dysfunction in pediatric cerebral malaria (CM) pathology. However, there is still limited understanding of how these complex inflammatory stimuli are integrated by brain endotheli...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Avril, Marion, Benjamin, Max, Dols, Mary-Margaret, Smith, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739390/
https://ncbi.nlm.nih.gov/pubmed/31511575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49530-1
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