Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence

Plasmodium falciparum malaria remains one of the most deadly infections worldwide. The pathogenesis of the infection results from the sequestration of infected erythrocytes (IRBC) in vital organs, including the brain, with resulting impairment of blood flow, hypoxia, and lactic acidosis. Sequestrati...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Gillrie, Mark R., Renaux, Bernard, Russell-Goldman, Eleanor, Avril, Marion, Brazier, Andrew J., Mihara, Koichiro, Di Cera, Enrico, Milner, Danny A., Hollenberg, Morley D., Smith, Joseph D., Ho, May
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021802/
https://ncbi.nlm.nih.gov/pubmed/27624125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01120-16
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