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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition

Racemases and epimerases catalyse changes in the stereochemical configurations of chiral centres and are of interest as model enzymes and as biotechnological tools. They also occupy pivotal positions within metabolic pathways and, hence, many of them are important drug targets. This review summarise...

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Vydáno v:Chem Soc Rev
Hlavní autoři: Lloyd, Matthew D., Yevglevskis, Maksims, Nathubhai, Amit, James, Tony D., Threadgill, Michael D., Woodman, Timothy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society of Chemistry 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142540/
https://ncbi.nlm.nih.gov/pubmed/34027955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cs00540a
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