Lataa...
Hypomethylation of a centromeric block of ICR1 is sufficient to cause Silver-Russell syndrome
Silver-Russell syndrome (SRS) is a representative imprinting disorder. A major cause is the loss of methylation (LOM) of imprinting control region 1 (ICR1) within the IGF2/H19 domain. ICR1 is a gametic differentially methylated region (DMR) consisting of two repeat blocks, with each block including...
Tallennettuna:
| Julkaisussa: | J Med Genet |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BMJ Publishing Group
2021
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8142445/ https://ncbi.nlm.nih.gov/pubmed/32447322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2020-106907 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|