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Permissive Transcriptional Activity at the Centromere through Pockets of DNA Hypomethylation
DNA methylation is a hallmark of transcriptional silencing, yet transcription has been reported at the centromere. To address this apparent paradox, we employed a fully sequence-defined ectopic human centromere (or neocentromere) to investigate the relationship between DNA methylation and transcript...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1361766/ https://ncbi.nlm.nih.gov/pubmed/16477312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020017 |
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